Benepali  Syringe



  • This is the BenepaliTM single-dose, pre-filled syringe.1
  • Stainless steel 27 gauge needle for more comfort.


The Benepali pre-filled syringe is for a subcutaneous injection. It should be injected into the thigh, abdomen, or back of the upper arm

Rotate the site for each injection.

If you are injecting into the abdomen, choose a site that is at least 5 cm away from the belly button.

  • Do not inject into areas that are red, hard, bruised, or tender.
  • Do not inject into scars or stretch marks.
  • If you have psoriasis, do not inject into any raised, thick, red, or scaly skin patches, or lesions.


  1. 1. Inspect the pre-filled syringe:

    Check the expiry date on the pre-filled syringe label.

    • Do not use the pre-filled syringe past the expiration date.
    • Do not use the pre-filled syringe if it has been dropped onto a hard surface. Components inside the pre-filled syringe may be broken.
    • Do not use the pre-filled syringe if the needle cap is missing or not securely attached.
  2. 2. Inspect the solution:

    Look at the medicine through the viewing window. The medicine should be clear to slightly opalescent, colourless or pale yellow, and may contain small white or almost transparent particles of protein.

    • Do not use the solution if it is discoloured, cloudy, or if particles other than those described above are present.
  3. 3. Allow the medicine to reach room temperature:

    Remove one pre-filled syringe from the carton that is stored in the refrigerator and leave at room temperature for at least 30 minutes before injecting.

    This is important to make the medicine easier and more comfortable to inject.

    • Do not remove the needle cap until you are ready to inject.
    • Do not use heat sources, such as a microwave or hot water, to warm Benepali.


Step 1.

Wash your hands with soap and water.

Step 2.

Wipe the skin at the injection site with an alcohol swab.

See 'Choose an injection site care' for guidance with choosing an injection site.

Do not touch this area again before giving the injection.

Step 3.

Pull the needle cover straight off and dispose of it in the bin or sharps container.

See 'Choose an injection site' for guidance with choosing an injection site.

Do not twist or bend the needle cover while removing it, as this may damage the needle.

Do not touch the plunger rod while removing the needle cover.

Never recap the needle.

Step 4.

Gently pinch a fold of skin at the cleaned injection site. Hold the pre-filled syringe at 45 degrees to the skin. With a quick, dart-like motion, insert the needle fully into the skin.

You can let go of the skin that you are pinching after the needle is completely inserted.

Step 5.

Slowly push down the plunger to inject all of the BenepallTM solution.

Step 6.

When the syringe is empty, remove the needle from the skin at the same angle as inserted.

Never recap the needle.

Recapping could lead to a needle stick injury.


Dispose of the entire syringe in an approved sharps container.

Check with your healthcare provider for instructions on how to properly dispose a filled sharps container.

Do not throw the sharps container in household bin.

Do not recycle.

Do not reuse the Benepali® pre-filled syringe.

Always keep the container out of the sight and reach of children.

lnjection site care

If there is bleeding at the injection site, press a gauze pad over the injection site.

• Do not rub the injection site.

If needed, cover the injection site with a plaster.